The aryl pyrazole integrated imidazole compounds 9a-g were synthesized by condensing 2-amino-N-methyl-5-ethyl carboxylate imidazole 7 with ethyl 5-methyl-1,3-diphenyl-1H-pyrazole-4-carboxylate 8a-g in presence of anhydrous potassium carbonate and dry acetone. Compounds 9a-g were screened against twelve human pathogens. Among them compound 9f exhibited maximum activity.
Loading....